METHODS FOR ENHANCING RECOMBINANT ADENO-ASSOCIATED VIRUS YIELD

The invention provides methods for the production of recombinant adeno-associated virus vectors (rAAV), comprising contacting a host cell with a solution comprising at least one compound of formula (I), (I-A), (I-B), (II), (III), or (IV), or a salt thereof, or a vitamin B, or any combination(s) ther...

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Bibliographische Detailangaben
Hauptverfasser: Fulco, Cameron Tage, Panteli, Jan Thomas, Hogan, Rachael C, Jiang, Mingyang, Allen, John Everett
Format: Patent
Sprache:eng
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Zusammenfassung:The invention provides methods for the production of recombinant adeno-associated virus vectors (rAAV), comprising contacting a host cell with a solution comprising at least one compound of formula (I), (I-A), (I-B), (II), (III), or (IV), or a salt thereof, or a vitamin B, or any combination(s) thereof. Also provided are methods for increasing the production of rAAV by a host cell, comprising contacting a host cell with a solution comprising at least one compound of formula (I), (I-A), (I-B), (II), (III), or (IV), or a salt thereof, or a vitamin B, or any combination(s) thereof.