SYNTHESIS OF METHYL 2-FLUOROACRYLATE

Methods for the synthesis of methyl 2-fluoroacrylate (MFA) are provided. The methods include use of various hydrofluorination agents using a variety of starting materials and reaction schemes. The methyl 2-fluoroacrylate prepared by the methods described herein can further be used to prepare patirom...

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Bibliographische Detailangaben
Hauptverfasser: Brunke, Jessica, Mu, Yongqi
Format: Patent
Sprache:eng
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Zusammenfassung:Methods for the synthesis of methyl 2-fluoroacrylate (MFA) are provided. The methods include use of various hydrofluorination agents using a variety of starting materials and reaction schemes. The methyl 2-fluoroacrylate prepared by the methods described herein can further be used to prepare patiromer calcium sorbitex.