LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND METHOD FOR DERIVERING ACTIVATORS TO CELL

The present embodiment provides a compound represented by the formula (1):Q-CHR2  (1)(Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids...

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Bibliographische Detailangaben
Hauptverfasser: ISHIHARA, Mitsuko, NOZAKI, Emi, NAITO, Katsuyuki, AKAHOSHI, Eiichi, SARUWATARI, Saeko
Format: Patent
Sprache:eng
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Zusammenfassung:The present embodiment provides a compound represented by the formula (1):Q-CHR2  (1)(Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells.