COMPOUND USED AS RET KINASE INHIBITOR AND APPLICATION THEREOF

The present invention relates to a compound used as an RET kinase inhibitor and an application thereof. The compound has a structure represented by formula F, has a good inhibitory ability for RET kinase, and has relatively good pharmacodynamic and pharmacokinetic performance, and lower toxic side e...

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Maolin, Liang, Apeng, Wu, Yusheng, Niu, Chengshan, Li, Jun
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a compound used as an RET kinase inhibitor and an application thereof. The compound has a structure represented by formula F, has a good inhibitory ability for RET kinase, and has relatively good pharmacodynamic and pharmacokinetic performance, and lower toxic side effects.