S1P RECEPTOR MODULATORS

The current invention is based on the determination that a S1P receptor modulator compound of formula (I):decreases the heart rate of a subject to which it is administered by about 5 beats/min or less daily, or about 4 beats/min or less daily, or about 3 beats/min or less daily, or about 2 beats/min...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GROBELNY, DAMIAN, GILL, GURMIT SINGH
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The current invention is based on the determination that a S1P receptor modulator compound of formula (I):decreases the heart rate of a subject to which it is administered by about 5 beats/min or less daily, or about 4 beats/min or less daily, or about 3 beats/min or less daily, or about 2 beats/min or less daily, wherein the S1P receptor modulator is administered at an initial daily dosage which is substantially the same as the standard daily therapeutic dosage.