DENDRIMER COMPOSITIONS AND THEIR USE IN TREATMENT OF DISEASES OF THE EYE

The present invention provides compositions comprising PAMAM dendrimers conjugated with one or more biologically active agents, and their use systemically to target activated microglia/macrophages in retina/choroid and generally, inflammatory and/or angiogenic diseases of the eye.

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Bibliographische Detailangaben
Hauptverfasser:	Kambhampati, Siva Pramodh, Rangaramanujam, Kannan, Mishra, Manoj, Lutty, Gerard, Bhutto, Imran
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides compositions comprising PAMAM dendrimers conjugated with one or more biologically active agents, and their use systemically to target activated microglia/macrophages in retina/choroid and generally, inflammatory and/or angiogenic diseases of the eye.