HOST CELLS AND THEIR USE FOR PRODUCING RIBITOL AND FURTHER MONOSACCHARIDES

The present invention relates to host cells and their use wherein the host cells are capable of producing D-ribulose and incapable of or have a reduced capability of converting D-ribulose to a molecule other than ribitol, wherein the host cells comprise a heterologous nucleic acid sequence encoding...

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Bibliographische Detailangaben
Hauptverfasser: MALCA, Sumire Honda, SCHÄFER, Astrid, CHANG, Yiming
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to host cells and their use wherein the host cells are capable of producing D-ribulose and incapable of or have a reduced capability of converting D-ribulose to a molecule other than ribitol, wherein the host cells comprise a heterologous nucleic acid sequence encoding a polypeptide capable of converting D-ribulose to ribitol with a cofactor preference for NADPH.