PROCESSES FOR PREPARING TUCATINIB POLYMORPHS

PROCESSES FOR PREPARING TUCATINIB POLYMORPHS

The present invention is directed to processes for making various polymorphs of tucatinib, designated herein as Form I, Form II, and Form III of tucatinib. These forms can then be used to prepare pharmaceutical formations containing tucatinib. Tucatinib is a tyrosine kinase inhibitor that is indicat...

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Hauptverfasser: WRIGHT, Mark Alexander, BONNAUD, Thierry, PATTERSON, Adam Ross, PRENTICE, Zoe
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Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator WRIGHT, Mark Alexander
BONNAUD, Thierry
PATTERSON, Adam Ross
PRENTICE, Zoe
description The present invention is directed to processes for making various polymorphs of tucatinib, designated herein as Form I, Form II, and Form III of tucatinib. These forms can then be used to prepare pharmaceutical formations containing tucatinib. Tucatinib is a tyrosine kinase inhibitor that is indicated for the treatment of breast cancer.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESSES FOR PREPARING TUCATINIB POLYMORPHS
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