ENGINEERED CLASS 2 TYPE V CRISPR SYSTEMS

Provided herein are engineered Class 2, Type V nucleases and guide RNAs useful for the editing of target nucleic acids. Also provided are methods of making and using such variants to modify nucleic acids.

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Bibliographische Detailangaben
Hauptverfasser:	STAAHL, Brett T, VIJAYAKUMAR, Gayathri, DENNY, Sarah, SIDORE, Angus, COLIN, Isabel, MAKHIJA, Suraj, HIGGINS, Sean, OAKES, Benjamin
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided herein are engineered Class 2, Type V nucleases and guide RNAs useful for the editing of target nucleic acids. Also provided are methods of making and using such variants to modify nucleic acids.