Method for Isolation of Cytisine

A method for isolating cytisine from plant material includes dissolving the plant material in an alcohol to form a liquid mixture and acidifying the liquid mixture by addition of an acid. The method also includes concentrating the liquid mixture to form a concentrated aqueous solution and extracting...

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Hauptverfasser:	Metodiev, Danail Georgiev, Apostolova, Petya Mitkova, Klisarova, Maria Nedkova, Stoyanov, Nikolay Kirilov, Zaekova, Galina Nikolova
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SEPARATION TRANSPORTING
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Beschreibung
Zusammenfassung:	A method for isolating cytisine from plant material includes dissolving the plant material in an alcohol to form a liquid mixture and acidifying the liquid mixture by addition of an acid. The method also includes concentrating the liquid mixture to form a concentrated aqueous solution and extracting the concentrated aqueous solution with a first extractant to form a purified aqueous concentrate. The method includes alkalizing the purified aqueous concentrate with an alkalizing agent to form an alkaline aqueous concentrate. The method further includes extracting the alkaline aqueous concentrate with a second extractant and removing the second extractant to obtain cytisine.