EXO-AZA SPIRO INHIBITORS OF MENIN-MLL INTERACTION
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MD...
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| creator | DAI, Xuedong KROSKY, Daniel Jason FU, Liqiang PONCELET, Virginie Sophie MORSCHHÄUSER GEB. HERKERT, Barbara LIU, Yingtao PANDE, Vineet EDWARDS, James Patrick CAI, Wei QUEROLLE, Olivier Alexis Georges WAN, Zhao-Kui KONG, Linglong PATRICK, Aaron Nathaniel ANGIBAUD, Patrick René |
| description | The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes. |
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HERKERT, Barbara</au><au>LIU, Yingtao</au><au>PANDE, Vineet</au><au>EDWARDS, James Patrick</au><au>CAI, Wei</au><au>QUEROLLE, Olivier Alexis Georges</au><au>WAN, Zhao-Kui</au><au>KONG, Linglong</au><au>PATRICK, Aaron Nathaniel</au><au>ANGIBAUD, Patrick René</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>EXO-AZA SPIRO INHIBITORS OF MENIN-MLL INTERACTION</title><date>2023-02-09</date><risdate>2023</risdate><abstract>The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | EXO-AZA SPIRO INHIBITORS OF MENIN-MLL INTERACTION |
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