EXO-AZA SPIRO INHIBITORS OF MENIN-MLL INTERACTION

The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MD...

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Bibliographische Detailangaben
Hauptverfasser:	DAI, Xuedong, KROSKY, Daniel Jason, FU, Liqiang, PONCELET, Virginie Sophie, MORSCHHÄUSER GEB. HERKERT, Barbara, LIU, Yingtao, PANDE, Vineet, EDWARDS, James Patrick, CAI, Wei, QUEROLLE, Olivier Alexis Georges, WAN, Zhao-Kui, KONG, Linglong, PATRICK, Aaron Nathaniel, ANGIBAUD, Patrick René
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.