CD38-BINDING AGENTS AND USES THEREOF

Among other things, the present disclosure provides compounds comprising antibody binding moieties and CD38-binding targeting moieties. In some embodiments, provided compounds recruit various types of antibodies to diseased cells such as cancer cells, and induce immune activities to kill such cells....

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Bibliographische Detailangaben
Hauptverfasser: BERBASOVA, Tetyana, WELSCH, Matthew Ernest, BUNIN, Anna, RASTELLI, Luca, ROSSI, Ann Marie K
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Among other things, the present disclosure provides compounds comprising antibody binding moieties and CD38-binding targeting moieties. In some embodiments, provided compounds recruit various types of antibodies to diseased cells such as cancer cells, and induce immune activities to kill such cells. Provided technologies are useful for treating various diseases including cancer.