Chimeric Antigen Receptor and Natural Killer Cells Expressing Same

The present invention provides a chimeric antigen receptor and natural killer cells expressing the same, and particularly, a chimeric antigen receptor (CAR) which includes an intracellular signaling domain including the whole or a portion of an OX40 ligand (CD252), thereby having excellent effects o...

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Bibliographische Detailangaben
Hauptverfasser:	Jung, Mi Young, Her, Jung Hyun, Gwon, Su Hyun, Lim, Ho Yong, Cho, Sung Yoo, Lee, Eun Sol, Won, Sung Yong, Kim, Han Sol, Hwang, Yu Kyeong, Kim, Hyun Ah
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides a chimeric antigen receptor and natural killer cells expressing the same, and particularly, a chimeric antigen receptor (CAR) which includes an intracellular signaling domain including the whole or a portion of an OX40 ligand (CD252), thereby having excellent effects of increasing anticancer activity of immune cells, and immune cells expressing the same.