SYSTEMS AND METHODS FOR OLIGOMERIC MOLECULAR MACHINES

Disclosed herein are oligomeric machines comprising a first oligomeric module having a first end and a second end, and a second oligomeric module having a first end and a second end; wherein the first end of the first oligomeric module is joined to the first end of the second oligomeric module; and...

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Bibliographische Detailangaben
Hauptverfasser: AVETISOV, Vladik, ILIEV, Roman
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein are oligomeric machines comprising a first oligomeric module having a first end and a second end, and a second oligomeric module having a first end and a second end; wherein the first end of the first oligomeric module is joined to the first end of the second oligomeric module; and wherein the oligomeric machine exhibits stochastic resonance and/or spontaneous vibrations in a solution at a temperature when the temperature is in a critical temperature range and the oligomeric machine does not exhibit stochastic resonance in the solution when the temperature is not in the critical temperature range; and the oligomeric machine exhibits stochastic resonance and/or spontaneous vibrations in a solution under a force load applied to the oligomeric machine when the force load is in a critical force range and the oligomeric machine does not exhibit stochastic resonance and/or spontaneous vibrations in the solution when the force load is not in the critical range. Also disclosed herein are molecular sensors comprising an oligomeric machine and configured to bind with one or more analytes thus modulating the stochastic resonance and/or spontaneous vibrations of the oligomeric machine. Additionally disclosed are uses of molecular sensors for the detection of one or more analytes in a solution.