4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF

4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF

The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SAKAMOTO, TOSHIHIRO, SCHÖPF, PATRICK, TWIGG, DAVID GEOFFREY, KONDO, HITOMI, EGASHIRA, NAOKI, SAGARA, TAKESHI, HAMLETT, CHRISTOPHER CHARLES FREDERICK, SUZUKI, TATSUYA, SHIBATA, KAZUAKI, SUGIMOTO, TETSUYA, YAMAMOTO, TOMOHIRO, ASAKURA, HIROKI, KAWAI, YUICHI, KATAOKA, YUKI
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator SAKAMOTO, TOSHIHIRO
SCHÖPF, PATRICK
TWIGG, DAVID GEOFFREY
KONDO, HITOMI
EGASHIRA, NAOKI
SAGARA, TAKESHI
HAMLETT, CHRISTOPHER CHARLES FREDERICK
SUZUKI, TATSUYA
SHIBATA, KAZUAKI
SUGIMOTO, TETSUYA
YAMAMOTO, TOMOHIRO
ASAKURA, HIROKI
KAWAI, YUICHI
KATAOKA, YUKI
description The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2023023023A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2023023023A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2023023023A13</originalsourceid><addsrcrecordid>eNrjZDAy0XX09fTzdwoN0TXSdfUDclxcFVxcgzzDHEM8w1yDFRz9XBSCHX1CghVCPFyDXP3deBhY0xJzilN5oTQ3g7Kba4izh25qQX58anFBYnJqXmpJfGiwkYGRMQQ5GhoTpwoA6nonWw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF</title><source>esp@cenet</source><creator>SAKAMOTO, TOSHIHIRO ; SCHÖPF, PATRICK ; TWIGG, DAVID GEOFFREY ; KONDO, HITOMI ; EGASHIRA, NAOKI ; SAGARA, TAKESHI ; HAMLETT, CHRISTOPHER CHARLES FREDERICK ; SUZUKI, TATSUYA ; SHIBATA, KAZUAKI ; SUGIMOTO, TETSUYA ; YAMAMOTO, TOMOHIRO ; ASAKURA, HIROKI ; KAWAI, YUICHI ; KATAOKA, YUKI</creator><creatorcontrib>SAKAMOTO, TOSHIHIRO ; SCHÖPF, PATRICK ; TWIGG, DAVID GEOFFREY ; KONDO, HITOMI ; EGASHIRA, NAOKI ; SAGARA, TAKESHI ; HAMLETT, CHRISTOPHER CHARLES FREDERICK ; SUZUKI, TATSUYA ; SHIBATA, KAZUAKI ; SUGIMOTO, TETSUYA ; YAMAMOTO, TOMOHIRO ; ASAKURA, HIROKI ; KAWAI, YUICHI ; KATAOKA, YUKI</creatorcontrib><description>The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230126&amp;DB=EPODOC&amp;CC=US&amp;NR=2023023023A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230126&amp;DB=EPODOC&amp;CC=US&amp;NR=2023023023A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SAKAMOTO, TOSHIHIRO</creatorcontrib><creatorcontrib>SCHÖPF, PATRICK</creatorcontrib><creatorcontrib>TWIGG, DAVID GEOFFREY</creatorcontrib><creatorcontrib>KONDO, HITOMI</creatorcontrib><creatorcontrib>EGASHIRA, NAOKI</creatorcontrib><creatorcontrib>SAGARA, TAKESHI</creatorcontrib><creatorcontrib>HAMLETT, CHRISTOPHER CHARLES FREDERICK</creatorcontrib><creatorcontrib>SUZUKI, TATSUYA</creatorcontrib><creatorcontrib>SHIBATA, KAZUAKI</creatorcontrib><creatorcontrib>SUGIMOTO, TETSUYA</creatorcontrib><creatorcontrib>YAMAMOTO, TOMOHIRO</creatorcontrib><creatorcontrib>ASAKURA, HIROKI</creatorcontrib><creatorcontrib>KAWAI, YUICHI</creatorcontrib><creatorcontrib>KATAOKA, YUKI</creatorcontrib><title>4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF</title><description>The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAy0XX09fTzdwoN0TXSdfUDclxcFVxcgzzDHEM8w1yDFRz9XBSCHX1CghVCPFyDXP3deBhY0xJzilN5oTQ3g7Kba4izh25qQX58anFBYnJqXmpJfGiwkYGRMQQ5GhoTpwoA6nonWw</recordid><startdate>20230126</startdate><enddate>20230126</enddate><creator>SAKAMOTO, TOSHIHIRO</creator><creator>SCHÖPF, PATRICK</creator><creator>TWIGG, DAVID GEOFFREY</creator><creator>KONDO, HITOMI</creator><creator>EGASHIRA, NAOKI</creator><creator>SAGARA, TAKESHI</creator><creator>HAMLETT, CHRISTOPHER CHARLES FREDERICK</creator><creator>SUZUKI, TATSUYA</creator><creator>SHIBATA, KAZUAKI</creator><creator>SUGIMOTO, TETSUYA</creator><creator>YAMAMOTO, TOMOHIRO</creator><creator>ASAKURA, HIROKI</creator><creator>KAWAI, YUICHI</creator><creator>KATAOKA, YUKI</creator><scope>EVB</scope></search><sort><creationdate>20230126</creationdate><title>4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF</title><author>SAKAMOTO, TOSHIHIRO ; SCHÖPF, PATRICK ; TWIGG, DAVID GEOFFREY ; KONDO, HITOMI ; EGASHIRA, NAOKI ; SAGARA, TAKESHI ; HAMLETT, CHRISTOPHER CHARLES FREDERICK ; SUZUKI, TATSUYA ; SHIBATA, KAZUAKI ; SUGIMOTO, TETSUYA ; YAMAMOTO, TOMOHIRO ; ASAKURA, HIROKI ; KAWAI, YUICHI ; KATAOKA, YUKI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2023023023A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SAKAMOTO, TOSHIHIRO</creatorcontrib><creatorcontrib>SCHÖPF, PATRICK</creatorcontrib><creatorcontrib>TWIGG, DAVID GEOFFREY</creatorcontrib><creatorcontrib>KONDO, HITOMI</creatorcontrib><creatorcontrib>EGASHIRA, NAOKI</creatorcontrib><creatorcontrib>SAGARA, TAKESHI</creatorcontrib><creatorcontrib>HAMLETT, CHRISTOPHER CHARLES FREDERICK</creatorcontrib><creatorcontrib>SUZUKI, TATSUYA</creatorcontrib><creatorcontrib>SHIBATA, KAZUAKI</creatorcontrib><creatorcontrib>SUGIMOTO, TETSUYA</creatorcontrib><creatorcontrib>YAMAMOTO, TOMOHIRO</creatorcontrib><creatorcontrib>ASAKURA, HIROKI</creatorcontrib><creatorcontrib>KAWAI, YUICHI</creatorcontrib><creatorcontrib>KATAOKA, YUKI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SAKAMOTO, TOSHIHIRO</au><au>SCHÖPF, PATRICK</au><au>TWIGG, DAVID GEOFFREY</au><au>KONDO, HITOMI</au><au>EGASHIRA, NAOKI</au><au>SAGARA, TAKESHI</au><au>HAMLETT, CHRISTOPHER CHARLES FREDERICK</au><au>SUZUKI, TATSUYA</au><au>SHIBATA, KAZUAKI</au><au>SUGIMOTO, TETSUYA</au><au>YAMAMOTO, TOMOHIRO</au><au>ASAKURA, HIROKI</au><au>KAWAI, YUICHI</au><au>KATAOKA, YUKI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF</title><date>2023-01-26</date><risdate>2023</risdate><abstract>The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2023023023A1
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title 4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T08%3A14%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SAKAMOTO,%20TOSHIHIRO&rft.date=2023-01-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2023023023A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true