4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF

The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.

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Bibliographische Detailangaben
Hauptverfasser:	SAKAMOTO, TOSHIHIRO, SCHÖPF, PATRICK, TWIGG, DAVID GEOFFREY, KONDO, HITOMI, EGASHIRA, NAOKI, SAGARA, TAKESHI, HAMLETT, CHRISTOPHER CHARLES FREDERICK, SUZUKI, TATSUYA, SHIBATA, KAZUAKI, SUGIMOTO, TETSUYA, YAMAMOTO, TOMOHIRO, ASAKURA, HIROKI, KAWAI, YUICHI, KATAOKA, YUKI
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.