Biological Tissue Access and Closure Apparatus, Systems and Methods

A tissue access and closure system for piercing through biological tissue and providing access to internal structures; particularly, intra-abdominal structures, and closing an opening in the tissue. The system includes a suture passer sub-system that is adapted to releasably secure sutures and insert the sutures into and through the tissue, and a suture guide sub-system that is adapted to cooperate with the suture passer sub-system, the cooperation including engaging and retaining sutures releasably secured to the suture passer sub-system after the sutures are inserted into and through the tissue with the suture passer sub-system, the suture passer sub-system and sutures are advanced into the suture guide sub-system, and the suture passer sub-system and sutures are subsequently withdrawn out of the suture guide sub-system.