RNA ACTION INHIBITOR AND USE THEREOF

An agent for inhibiting the action of a target RNA based on RNA interference and ASO with a passenger strand and a guide strand for a target RNA, wherein both ends of double-stranded RNA formed pairing of the passenger strand and the guide strand are blunt ends, and one or two or more selected from...

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Bibliographische Detailangaben
Hauptverfasser:	MURAYAMA, Keiji, ASANUMA, Hiroyuki, MATSUMOTO, Masanori, MARUYAMA, Shoichi, TSUBOI, Toshiki, KOTO, Ayako, KOKURYO, Toshio, YUGUCHI, Motoki, DOKE, Tomohito, ASAI, Ryoichi, ISHIMOTO, Takuji, ISHIMARU, Isao, SUGITA, Tomoe, KATO, Yukiko, NAKASHA, Ayaka, NISHI, Keisuke
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	An agent for inhibiting the action of a target RNA based on RNA interference and ASO with a passenger strand and a guide strand for a target RNA, wherein both ends of double-stranded RNA formed pairing of the passenger strand and the guide strand are blunt ends, and one or two or more selected from the group consisting of the units represented by formula (1) and formula (2) below at the following positions (a) and (b): (a) 5′ end side and 3′ end side of the passenger strand, (b) 3′ end side of the guide strand(in which X represents an oxygen atom or sulfur atom),(in which X represents an oxygen atom or sulfur atom).