METHODS OF ASSESSING AND MONITORING TUMOR LOAD

The invention disclosed herein generally relates to methods of assessing and monitoring tumor load through analysis of tumor DNA in cancer patients. Quantitative measures derived from cell-free DNA and germline DNA are used to assess and monitor tumor load. By assessing and monitoring tumor load, ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SPINOSA, John C, LEVY, Samuel
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention disclosed herein generally relates to methods of assessing and monitoring tumor load through analysis of tumor DNA in cancer patients. Quantitative measures derived from cell-free DNA and germline DNA are used to assess and monitor tumor load. By assessing and monitoring tumor load, cancer may be detected in a subject. The tumor load of a subject may be assessed at a number of different time points to monitor a progression, regression, or recurrence of cancer in a subject.