BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE

Described herein are bifunctional degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment of conditions, diseases, and disorders mediated by various target proteins.

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Bibliographische Detailangaben
Hauptverfasser: ARISTA, Luca, DOUMAMPOUOM-METOUL, Lionel, LORBER, Julien, JEULIN, Ingrid Karen Jennifer, HEBACH, Christina, YAMADA, Ken, GOUDE, Marie-Line, ZOLLER, Thomas, D'ALESSANDRO, Pier Luca, MA, Fupeng, VULPETTI, Anna, BROENNIMANN, Valerie, KIRMAN, Louise Clare, HOLLINGWORTH, Gregory John
Format: Patent
Sprache:eng
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Zusammenfassung:Described herein are bifunctional degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment of conditions, diseases, and disorders mediated by various target proteins.