LOCUS SPECIFIC AMPLIFICATION USING ARRAY PROBES

Methods are provided for multiplexed amplification of selected targets and analysis of the amplified targets. In preferred aspects the amplification and analysis take place on the same solid support and preferably in a localized area such as a bead or a feature of an array. In preferred aspects the...

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Bibliographische Detailangaben
Hauptverfasser: SHAPERO, Michael, FU, Glenn, WANG, Pei-Hua
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods are provided for multiplexed amplification of selected targets and analysis of the amplified targets. In preferred aspects the amplification and analysis take place on the same solid support and preferably in a localized area such as a bead or a feature of an array. In preferred aspects the analysis is a determination of sequence at one or more locations in the amplified target. The methods may be used for genotyping, sequencing and analysis of copy number.