METHOD FOR PRODUCING PEPTIDE COMPOUND

An object of the present invention is to provide a method for producing a peptide with high efficiency, and a method for producing a peptide which comprises the following steps (1) and (2):(1) a step of mixing an N-protected amino acid or an N-protected peptide with a carboxylic acid halide represen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MORODOME, Keisuke, HANDA, Michiharu
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:An object of the present invention is to provide a method for producing a peptide with high efficiency, and a method for producing a peptide which comprises the following steps (1) and (2):(1) a step of mixing an N-protected amino acid or an N-protected peptide with a carboxylic acid halide represented by the formula (I)(wherein X represents a halogen atom,R1, R2 and R3 each independently represent an aliphatic hydrocarbon group which may have a substituent, and a total number of the carbon atoms in R1, R2 and R3 is 3 to 40); and(2) a step of mixing the product obtained in the step (1) and a C-protected amino acid or a C-protected peptideis provided.