IMMOBILIZED POLY(N)POLYMERASE

The present invention relates to an immobilized poly(N)polymerase (PNP), methods of producing said PNP and uses thereof. Further disclosed is an enzyme reactor and kit comprising the PNP for producing polynucleotidylated ribonucleic acid (poly(N)RNA) molecules which are useful in gene therapy, immun...

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Bibliographische Detailangaben
Hauptverfasser: YAZDAN PANAH, Benyamin, ROOS, Tilmann, CONZELMANN, Markus, WAGNER, Veronika
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to an immobilized poly(N)polymerase (PNP), methods of producing said PNP and uses thereof. Further disclosed is an enzyme reactor and kit comprising the PNP for producing polynucleotidylated ribonucleic acid (poly(N)RNA) molecules which are useful in gene therapy, immunotherapy, protein replacement therapy and/or vaccination.