BLOCKADE OF CD7 EXPRESSION AND CHIMERIC ANTIGEN RECEPTORS FOR IMMUNOTHERAPY OF T-CELL MALIGNANCIES

The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.

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Bibliographische Detailangaben
Hauptverfasser: Campana, Dario, Kamiya, Takahiro, Vinanica, Natasha, Png, Yi Tian
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.