COMPOSITIONS AND METHODS OF DETECTING ANALYTES

A composition and method of detecting an analyte in a sample using the composition, the composition including: a liquid that includes water; a plurality of first hollow glass bubbles in the liquid; a plurality of covalently attached first affinity groups that are covalently attached to at least some...

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Bibliographische Detailangaben
Hauptverfasser: Sgolastra, Frederica, Nakamura, Masayuki, Kalstabakken, Kyle A, Horton, Leslie M, Kennedy, Stephen M, Bothof, Catherine A, Roscoe, Stephen B, Johnson, David D, Dai, Minghua, Kang, Myungchan, Dohmeier, Daniel M, Yuksel Yurt, Deniz, Percy, Neil
Format: Patent
Sprache:eng
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Zusammenfassung:A composition and method of detecting an analyte in a sample using the composition, the composition including: a liquid that includes water; a plurality of first hollow glass bubbles in the liquid; a plurality of covalently attached first affinity groups that are covalently attached to at least some of the plurality of first hollow glass bubbles; and a plurality of first detector compound molecules not covalently bonded to the plurality of first hollow glass bubbles; wherein the first detector compound molecules include a first detectable group that is detected at a first wavelength; and wherein the first hollow glass bubbles have: a density of less than 0.60 gram/mole; a span of less than 1.0; and a plurality of covalently attached first affinity groups.