Disposable Multiple Needle Biopsy Instrument and Needle Guide

Multiple needle biopsy instruments, guides, and systems and methods for forming and using the same are disclosed. In some embodiments, the multiple needle biopsy instrument can include a handle, a first needle and second needle, an inner core platform, an outer sheath platform, and a set of trigger mechanism controls. The first and second needles can include inner cores formed with tissue notches, and outer sheaths. The inner core and outer sheath platforms can be joined to the inner cores and outer sheaths, and coupled to inner core and outer sheath springs. The set of trigger mechanism controls can control movement of the inner core and outer sheath platforms as well as the inner core and outer sheath springs. Releasing the inner core and outer sheath springs causes the outer sheaths and inner core to eject such that tissue cut by the outer sheath is deposited into the tissue notches.