PYRROLOBENZODIAZEPINE ANTIBODY CONJUGATES
The present disclosure relates generally to antibody-drug conjugates comprising pyrrolo[2, 1-c][1, 4]benzodiazepine (PBD) drug moieties. The present disclosure also relates to methods of using these conjugates, e.g., as therapeutics and/or diagnostics.
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| creator | KELLEHER, Eugene W THOMAS, Joshua D YURKOVETSKIY, Aleksandr V JONES, Brian D YIN, Mao LOWINGER, Timothy B YANG, Liping |
| description | The present disclosure relates generally to antibody-drug conjugates comprising pyrrolo[2, 1-c][1, 4]benzodiazepine (PBD) drug moieties. The present disclosure also relates to methods of using these conjugates, e.g., as therapeutics and/or diagnostics. |
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| subjects | CHEMISTRY COMPOUNDS OF UNKNOWN CONSTITUTION HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | PYRROLOBENZODIAZEPINE ANTIBODY CONJUGATES |
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