METHOD FOR CONTINUOUSLY PRODUCING AN ACTIVE INGREDIENT GRANULATE
A method for the continuous production of an active ingredient granulate is provided, which comprises the following steps:(a) preparing a spray composition by dissolving or dispersing an active ingredient and optionally one or more excipients in a liquid;(b) providing solid particles in a process sp...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | NOWAK, Reinhard GRAVE, Annette PÖLLINGER, Norbert JACOB, Michael |
| description | A method for the continuous production of an active ingredient granulate is provided, which comprises the following steps:(a) preparing a spray composition by dissolving or dispersing an active ingredient and optionally one or more excipients in a liquid;(b) providing solid particles in a process space;(c) introducing droplets of the spray composition into an injection zone of the process space in which the liquid evaporates;(d) repeatedly guiding the solid particles back past the sprayed droplets in the process space with the aid of a process gas jet, so that at least a portion of the droplets, which may have already lost part of the liquid contained, comes into contact with solid particles and larger solid particles are formed through agglomeration;(e) removing the active ingredient granulate from the process space in the form of solid particles,wherein the active ingredient in the form used has a Hausner factor of 1.19 or greater. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2022280432A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2022280432A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2022280432A13</originalsourceid><addsrcrecordid>eNrjZHDwdQ3x8HdRcPMPUnD29wvx9Av1Dw32iVQICPJ3CXX29HNXcPRTcHQO8QxzVQDyglxdPF39QhTcgxz9Qn0cQ1x5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8aLCRgZGRkYWBibGRo6ExcaoAepgr0w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHOD FOR CONTINUOUSLY PRODUCING AN ACTIVE INGREDIENT GRANULATE</title><source>esp@cenet</source><creator>NOWAK, Reinhard ; GRAVE, Annette ; PÖLLINGER, Norbert ; JACOB, Michael</creator><creatorcontrib>NOWAK, Reinhard ; GRAVE, Annette ; PÖLLINGER, Norbert ; JACOB, Michael</creatorcontrib><description>A method for the continuous production of an active ingredient granulate is provided, which comprises the following steps:(a) preparing a spray composition by dissolving or dispersing an active ingredient and optionally one or more excipients in a liquid;(b) providing solid particles in a process space;(c) introducing droplets of the spray composition into an injection zone of the process space in which the liquid evaporates;(d) repeatedly guiding the solid particles back past the sprayed droplets in the process space with the aid of a process gas jet, so that at least a portion of the droplets, which may have already lost part of the liquid contained, comes into contact with solid particles and larger solid particles are formed through agglomeration;(e) removing the active ingredient granulate from the process space in the form of solid particles,wherein the active ingredient in the form used has a Hausner factor of 1.19 or greater.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220908&DB=EPODOC&CC=US&NR=2022280432A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220908&DB=EPODOC&CC=US&NR=2022280432A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NOWAK, Reinhard</creatorcontrib><creatorcontrib>GRAVE, Annette</creatorcontrib><creatorcontrib>PÖLLINGER, Norbert</creatorcontrib><creatorcontrib>JACOB, Michael</creatorcontrib><title>METHOD FOR CONTINUOUSLY PRODUCING AN ACTIVE INGREDIENT GRANULATE</title><description>A method for the continuous production of an active ingredient granulate is provided, which comprises the following steps:(a) preparing a spray composition by dissolving or dispersing an active ingredient and optionally one or more excipients in a liquid;(b) providing solid particles in a process space;(c) introducing droplets of the spray composition into an injection zone of the process space in which the liquid evaporates;(d) repeatedly guiding the solid particles back past the sprayed droplets in the process space with the aid of a process gas jet, so that at least a portion of the droplets, which may have already lost part of the liquid contained, comes into contact with solid particles and larger solid particles are formed through agglomeration;(e) removing the active ingredient granulate from the process space in the form of solid particles,wherein the active ingredient in the form used has a Hausner factor of 1.19 or greater.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHDwdQ3x8HdRcPMPUnD29wvx9Av1Dw32iVQICPJ3CXX29HNXcPRTcHQO8QxzVQDyglxdPF39QhTcgxz9Qn0cQ1x5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8aLCRgZGRkYWBibGRo6ExcaoAepgr0w</recordid><startdate>20220908</startdate><enddate>20220908</enddate><creator>NOWAK, Reinhard</creator><creator>GRAVE, Annette</creator><creator>PÖLLINGER, Norbert</creator><creator>JACOB, Michael</creator><scope>EVB</scope></search><sort><creationdate>20220908</creationdate><title>METHOD FOR CONTINUOUSLY PRODUCING AN ACTIVE INGREDIENT GRANULATE</title><author>NOWAK, Reinhard ; GRAVE, Annette ; PÖLLINGER, Norbert ; JACOB, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2022280432A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2022</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>NOWAK, Reinhard</creatorcontrib><creatorcontrib>GRAVE, Annette</creatorcontrib><creatorcontrib>PÖLLINGER, Norbert</creatorcontrib><creatorcontrib>JACOB, Michael</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NOWAK, Reinhard</au><au>GRAVE, Annette</au><au>PÖLLINGER, Norbert</au><au>JACOB, Michael</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR CONTINUOUSLY PRODUCING AN ACTIVE INGREDIENT GRANULATE</title><date>2022-09-08</date><risdate>2022</risdate><abstract>A method for the continuous production of an active ingredient granulate is provided, which comprises the following steps:(a) preparing a spray composition by dissolving or dispersing an active ingredient and optionally one or more excipients in a liquid;(b) providing solid particles in a process space;(c) introducing droplets of the spray composition into an injection zone of the process space in which the liquid evaporates;(d) repeatedly guiding the solid particles back past the sprayed droplets in the process space with the aid of a process gas jet, so that at least a portion of the droplets, which may have already lost part of the liquid contained, comes into contact with solid particles and larger solid particles are formed through agglomeration;(e) removing the active ingredient granulate from the process space in the form of solid particles,wherein the active ingredient in the form used has a Hausner factor of 1.19 or greater.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US2022280432A1 |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | METHOD FOR CONTINUOUSLY PRODUCING AN ACTIVE INGREDIENT GRANULATE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-19T00%3A35%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=NOWAK,%20Reinhard&rft.date=2022-09-08&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2022280432A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |