METHODS OF ANALYZING NUCLEIC ACIDS

Presented herein are methods and compositions for analyzing rare nucleic acid species. Some methods presented herein use DNA reassociation kinetics following thermal denaturation to define populations of nucleic acid sequences, e.g., highly abundant (e.g., cDNA from rRNA), moderately abundant, and l...

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Bibliographische Detailangaben
Hauptverfasser: Radek, Agnes, Kuersten, Scott, Vaidyanathan, Ramesh, Grunenwald, Haiying Li
Format: Patent
Sprache:eng
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Zusammenfassung:Presented herein are methods and compositions for analyzing rare nucleic acid species. Some methods presented herein use DNA reassociation kinetics following thermal denaturation to define populations of nucleic acid sequences, e.g., highly abundant (e.g., cDNA from rRNA), moderately abundant, and less abundant or rare sequences (e.g., cDNA from mRNA).