ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS

ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS

The present invention covers new isoquinoline compounds of general formula (I):in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising sai...

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Bibliographische Detailangaben
Hauptverfasser: BOEHM, Claudia, KULKE, Daniel, ALIG, Bernd, GRIEBENOW, Nils, HEISLER, Iring, SCHWARZ, Hans-Georg, HUEBSCH, Walter, ZHUANG, Wei, JANSSEN, Isa Jana Irina, BOERNGEN, Kirsten
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention covers new isoquinoline compounds of general formula (I):in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.