COMPOSITIONS AND METHODS FOR TREATING MYOCARDIUM WITH MESENCHYMAL STEM CELL SCAFFOLD

Disclosed are methods of increasing cardiac function in a subject's myocardium comprising: administering a scaffold to the subject's myocardium, wherein the scaffold comprises mesenchymal stem cells (MSCs). Disclosed are methods of restoring the mitochondrial proteome in a subject's m...

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Bibliographische Detailangaben
Hauptverfasser: Wright, Christin, Hocum Stone, Laura Leigh, Kelly, Rosemary Frances, McFalls, Edward Oakley
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed are methods of increasing cardiac function in a subject's myocardium comprising: administering a scaffold to the subject's myocardium, wherein the scaffold comprises mesenchymal stem cells (MSCs). Disclosed are methods of restoring the mitochondrial proteome in a subject's myocardium comprising: administering a scaffold to the subject's myocardium, wherein the scaffold comprises mesenchymal stem cells. Disclosed are methods of treating hibernating myocardium comprising combining surgical revascularization with attaching a scaffold comprising MSCs to myocardium.