SERUM-FREE CELL CULTURE MEDIUM

The specification describes an improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Ornithine, or a combination of ornithine and putrescine can be added to serum-free media or chemically defined media to improve viable cell density, to reduce ce...

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Bibliographische Detailangaben
Hauptverfasser: OSHODI, Shadia Abike, JOHNSON, Amy S, LAWRENCE, Shawn M
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The specification describes an improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Ornithine, or a combination of ornithine and putrescine can be added to serum-free media or chemically defined media to improve viable cell density, to reduce cell doubling time, and to increase the production of a protein of interest.