CD79B CHIMERIC ANTIGEN RECEPTORS

The invention provides improved compositions for adoptive cell therapies for cancers that express CD79B. The present invention relates to improved compositions and methods for treating cancer. More particularly, the invention relates to improved anti-CD79B chimeric antigen receptors (CARs), genetica...

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Bibliographische Detailangaben
Hauptverfasser:	PERKINS, Molly Reed, FRIEDMAN, Kevin
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention provides improved compositions for adoptive cell therapies for cancers that express CD79B. The present invention relates to improved compositions and methods for treating cancer. More particularly, the invention relates to improved anti-CD79B chimeric antigen receptors (CARs), genetically modified immune effector cells, and use of these compositions to effectively treat CD79B expressing cancers.