METHANOL UTILIZATION

Described herein are enzymes, such as for example, methanol dehydrogenase (MDH), 3-hexulose-6-phosphate isomerase (PHI), 3-hexulose-6-phosphate synthase (HPS), ribose-5-phosphate isomerase (RPI), ribulose 5-phosphate 3-epimerase (RPE), transketolase (TKT), transaldolase (TAL) enzymes, phosphofructok...

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Bibliographische Detailangaben
Hauptverfasser: Perli, Thomas, Florez, Sergio L, Abe, Kennji, Asahara, Takayuki, Putman, Ryan J, Takeshita, Ryo, Yamada, Kazuteru, Napolitano, Micjael G, Uehara, Yuri, Chinen, Akito, Ito, Yoshihiro, Zhou, Hui, Merighi, Massimo
Format: Patent
Sprache:eng
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Zusammenfassung:Described herein are enzymes, such as for example, methanol dehydrogenase (MDH), 3-hexulose-6-phosphate isomerase (PHI), 3-hexulose-6-phosphate synthase (HPS), ribose-5-phosphate isomerase (RPI), ribulose 5-phosphate 3-epimerase (RPE), transketolase (TKT), transaldolase (TAL) enzymes, phosphofructokinase (PFK), Sedoheptulose 1,7-Bisphosphatase (GLPX), fructose-bisphosphate aldolase (FBA), 6-phosphogluconate dehydrogenase (GND), and glucose-6-phosphate dehydrogenase (ZWF); recombinant host cells expressing the enzymes; methods of producing methylotrophic cells; and methods of producing amino acids (e.g., lysine).