Apparatus for Pathogen Detection

An apparatus for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. Th...

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Bibliographische Detailangaben
Hauptverfasser: Reed, Mark A, Montanaro Ochoa, Hazael Fabrizio, Weber, Monika, Lo, Siu Lung, Yerino, Christopher Daniel
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:An apparatus for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. A detection method for separating and analyzing a contaminant using the apparatus allows for transporting a test sample having an analyte and a waste product through at least one microfluidic channel; generating dielectrophoretic forces on the test sample as the test sample is transported through the at least one microfluidic channel; trapping the test sample to separate the waste product from the analyte; separating the waste product from the analyte; and sensing, with a sensor, the analyte