INHALED POWDER FORMULATIONS

Compounds of Formula (00A) and salts thereof, wherein R1, R2 R3, R4 and n are defined herein, are useful as inhibitors of one or more Janus kinases. Also provided are pharmaceutical compositions that include a compound of Formula (00A) and a pharmaceutically acceptable carrier, adjuvant or vehicle,...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Yun-Xing, Zak, Mark Edward, Gibbons, Paul, Kellar, Terry, Zhang, Lei, Li, Wei, Mendonca, Rohan, Yuen, Po-wai
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds of Formula (00A) and salts thereof, wherein R1, R2 R3, R4 and n are defined herein, are useful as inhibitors of one or more Janus kinases. Also provided are pharmaceutical compositions that include a compound of Formula (00A) and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient.