PHARMACEUTICAL, PHYTO-CANNABINOID BASED COMPOSITIONS

The present invention relates to a pharmaceutical composition comprising a combination of the cannabinoids tetrahydrocannabivarin (THCV), cannabigerol (CBG), cannabichromene (CBC) and tetrahydrocannabinol (THC) for use in the prevention or treatment of disorders related to depression, fatigue, deteriorated alertness, excessive daytime sleepiness and reduced appetite, wherein the relative weight ratios of THCV:CBG:CBC:THC are between 1-10:1-10:1-10:1-10, and to a method of treating a mammal in need thereof, said mammal suffering from a disorder related to depression, fatigue, deteriorated alertness, excessive daytime sleepiness and reduced appetite, wherein a combination of an effective amount of cannabinoids selected from the group consisting of tetrahdrocannabivarin (THCV), cannabigerol (CBG), cannabichromene (CBC) and tetrahydrocannabinol (THC), is administered to said mammal, wherein the relative weight ratios of THCV:CBG:CBC:THC are between 1-10:1-10:1-10:1-10.