(AZA)Benzothiazolyl Substituted Pyrazole Compounds

This application includes a compound of Formula Ior a pharmaceutically acceptable salt thereof; wherein the variables R1a, R1b, R2, R3, X, Y and Z are as defined herein, pharmaceutical compositions comprising the compounds of Formula I and methods of treatment comprising administering to a patient i...

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Bibliographische Detailangaben
Hauptverfasser: Wisniewska, Hanna Maria, Tu, Meihua Mike, Cabral, Shawn, Canterbury, Daniel Paul, Mascitti, Vincent, Korczynska, Magdalena, Shavnya, Andre, Wang, Tao, Dow, Robert Lee, Lavergne, Sophie Yvette, Londregan, Allyn Timothy, Fensome, Andrew, Piotrowski, David Walter
Format: Patent
Sprache:eng
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Zusammenfassung:This application includes a compound of Formula Ior a pharmaceutically acceptable salt thereof; wherein the variables R1a, R1b, R2, R3, X, Y and Z are as defined herein, pharmaceutical compositions comprising the compounds of Formula I and methods of treatment comprising administering to a patient in need thereof a compound of Formula I for the treatment of transthyretin amyloidosis and diseases related thereto.