METHODS AND COMPOSITIONS FOR TREATING MOTOR NEURON DISEASES

METHODS AND COMPOSITIONS FOR TREATING MOTOR NEURON DISEASES

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, includi...

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Bibliographische Detailangaben
Hauptverfasser: ESTRELA ARIGÜEL, José María, DELLINGER, Ryan W, OBRADOR PLA, María Elena, SALVADOR, Rosario
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, including a PDE4 inhibitor such as ibudilast, and also including a thiol/cysteine donor, such as acetylcysteine.