MACHINE LEARNING QUANTIFICATION OF TARGET ORGANISMS USING NUCLEIC ACID AMPLIFICATION ASSAYS

In some examples, a system for amplifying and quantifying a target organism present in a sample includes a detection device configured to amplify and detect a nucleic acid associated with the target organism. The detection device configured to receive a sample and to amplify nucleic acid in the samp...

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Bibliographische Detailangaben
Hauptverfasser: Rajagopal, Raj, Taghvaeeyan, Saber, Dominguez-Nunez, Wilfredo, Asendorf, Nicholas A
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:In some examples, a system for amplifying and quantifying a target organism present in a sample includes a detection device configured to amplify and detect a nucleic acid associated with the target organism. The detection device configured to receive a sample and to amplify nucleic acid in the sample over an amplification cycle. The detection device is configured to capture a data set including measurements of the nucleic acid collected during the amplification cycle. The system further includes a computing device configured to receive the data set and to apply a machine learning system to the data set. The machine learning system is trained to estimate a quantity of the target organism present in the sample based on the measurements in the data set.