Cognate Foldase Co-Expression

The present invention relates to means and methods for optimizing expression of a heterologous polypeptide of interest in Gram-positive host cells by co-expression with a foldase that is cognate to the heterologous polypeptide of interest.

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Bibliographische Detailangaben
Hauptverfasser: Ganuza, Ane Quesada, Nielsen, Allan Kent, Rasmussen, Michael Dolberg
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to means and methods for optimizing expression of a heterologous polypeptide of interest in Gram-positive host cells by co-expression with a foldase that is cognate to the heterologous polypeptide of interest.