ENHANCED PROTEIN PURIFICATION THROUGH A MODIFIED PROTEIN A ELUTION

ENHANCED PROTEIN PURIFICATION THROUGH A MODIFIED PROTEIN A ELUTION

The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KEBA, Asha Nandini-Radhamohan, BROWN, Arick, DOWD, Christopher J
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.