PaCas9 nuclease

The present invention relates to the field of biotechnology, molecular biology and medicine, in particular to nuclease enzyme and use thereof. More specifically, the present invention relates to PaCas9 nuclease enzyme. The invention also relates to a nucleic acid encoding said nuclease, a genetic co...

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Hauptverfasser: MADERA, Dmitriy Aleksandrovich, POBEGALOV, Georgii Evgenevich, VASILEVA, Aleksandra Andreevna, KARABELSKII, Aleksandr Vladimirovich, SELKOVA, Polina Anatolevna, SEVERINOV, Konstantin Viktorovich, FEDOROVA, Iana Vitalevna, SHMAKOV, Sergey Anatolevich, MOROZOV, Dmitry Valentinovich, ZYUBKO, Tatyana Igorevna, ARSENIEV, Anatolii Nikolaevich, SUTORMIN, Dmitrii Aleksandrovich, IVANOV, Roman Alekseevich
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to the field of biotechnology, molecular biology and medicine, in particular to nuclease enzyme and use thereof. More specifically, the present invention relates to PaCas9 nuclease enzyme. The invention also relates to a nucleic acid encoding said nuclease, a genetic construct, an expression vector, a delivery vector, which comprise said nucleic acid, a liposome comprising said nuclease or nucleic acid encoding said nuclease, a method for producing a nuclease, methods for delivery, and a host cell comprising a nucleic acid encoding said nuclease.