PYRIMIDINYL-HETEROARYLOXY-NAPHTHYL COMPOUNDS AND METHODS OF USE

Described herein are phenoxy-pyridazinyl-pyrimidine or phenoxy-pyrimidinyl-pyrimidine compounds and pharmaceutically acceptable salts thereof for use in the treatment of Ire1-mediated diseases and cancer.

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Bibliographische Detailangaben
Hauptverfasser:	Ly, Cuong Q, Ashkenazi, Avi, Wang, Fei, Beveridge, Ramsay, Braun, Marie-Gabrielle, Lai, Kwong Wah, Zhao, Liang, Rudolph, Joachim, Lee, Wendy, Gibbons, Paul, Fu, Leo, Lemire, Alexandre, Schwarz, Jacob Bradley
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	Described herein are phenoxy-pyridazinyl-pyrimidine or phenoxy-pyrimidinyl-pyrimidine compounds and pharmaceutically acceptable salts thereof for use in the treatment of Ire1-mediated diseases and cancer.