CONJUGATES AND NANOPARTICLES OF HYALURONIC ACID AND EPIGALLOCATECHIN-3-O-GALLATE AND USES THEREOF

CONJUGATES AND NANOPARTICLES OF HYALURONIC ACID AND EPIGALLOCATECHIN-3-O-GALLATE AND USES THEREOF

Disclosed herein is a nanoparticle composition comprising nanoparticles formed from one of: a conjugate of dimeric epigallocatechin-3-O-gallate and hyaluronic acid; a conjugate of epigallocatechin-3-O-gallate and hyaluronic acid; or a epigallocate-chin-3-O-gallate-terminated hyaluronic acid conjugat...

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Bibliographische Detailangaben
Hauptverfasser: Lai, Fritz, Yongvongsoontorn, Nunnarpas, Her, Zhisheng, Osato, Motomi, Chung, Joo Eun, Kurisawa, Motoichi, Liang, Kun, Chen, Qingfeng, Bae, Ki Hyun
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed herein is a nanoparticle composition comprising nanoparticles formed from one of: a conjugate of dimeric epigallocatechin-3-O-gallate and hyaluronic acid; a conjugate of epigallocatechin-3-O-gallate and hyaluronic acid; or a epigallocate-chin-3-O-gallate-terminated hyaluronic acid conjugate; and an active agent or a pharmaceutically acceptable salt, solvate or prodrug 0thereof suitable to treat acute myeloid leukaemia, wherein the active agent is encapsulated in the nanoparticles.