METHOD OF REDUCING AROMATIC NITRO COMPOUNDS

A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.

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Bibliographische Detailangaben
Hauptverfasser: DOMINGUEZ, Beatriz, BISAGNI, Serena, TEDROW, Jason, HEDLEY, Simon J, PUSHPANATH, Ahir, LEPAIH, Jacques, SLABU, Iustina, MENNEN, Steven M, BORNADEL, Amin
Format: Patent
Sprache:eng
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Zusammenfassung:A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.