Preparation Method for Amide Compounds and Use Thereof in Medical Field

Preparation Method for Amide Compounds and Use Thereof in Medical Field

Provided are a preparation method for amide compounds and use thereof in medical field. Specifically, provided are small molecule amide compounds. Such compounds are inhibitors of enhancer homolog 2 (EZH2) of Zeste gene, and can be used for preventing and/or treating related diseases mediated by EZH...

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Hauptverfasser: GE, Jian, ZHANG, Zhen, ZHANG, Yuyun, ZANG, Chengxu, XIA, Xiaoer, LI, Yunfei, YU, Hao, CHEN, Jia, WU, Qimei, XU, Xin, JIANG, Qingyun, ZHANG, Xiaojuan, WANG, Yijin, ZHOU, Xiaobo, GUO, Fengying, SUN, Kang, ZHANG, Liming
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided are a preparation method for amide compounds and use thereof in medical field. Specifically, provided are small molecule amide compounds. Such compounds are inhibitors of enhancer homolog 2 (EZH2) of Zeste gene, and can be used for preventing and/or treating related diseases mediated by EZH2, including tumors, myeloproliferative diseases or autoimmune diseases.