CD47 ANTIBODY, PREPARATION METHOD THEREFOR AND USES THEREOF

CD47 ANTIBODY, PREPARATION METHOD THEREFOR AND USES THEREOF

An antibody targeting CD47, a preparation method therefor and uses thereof. A novel mouse or human-mouse chimeric antibody targeting CD47. A method for preparing the monoclonal antibody. The monoclonal antibody of the present invention can bind CD47 antigen with high specificity, has high affinity a...

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Bibliographische Detailangaben
Hauptverfasser: GAO, Jing, DUAN, Qing, WANG, Dongxu, WANG, Mengying, YANG, Tatchi Teddy, PAN, Mingming, ZHAO, Jiaxun, KHAN, Shireen, XU, Zhiqiang, GUO, Cuicui, LIU, Lile, ZHOU, Wenming, TONG, Guozhen, XIA, Ke, WANG, Lu, YAO, Jingyun, DAI, Chaohui, MENG, Yali, WANG, Liang
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:An antibody targeting CD47, a preparation method therefor and uses thereof. A novel mouse or human-mouse chimeric antibody targeting CD47. A method for preparing the monoclonal antibody. The monoclonal antibody of the present invention can bind CD47 antigen with high specificity, has high affinity and significant activities, such as anti-tumor activity.