POLYNUCLEOTIDE FOR SAFER AND MORE EFFECTIVE IMMUNOTHERAPIES

POLYNUCLEOTIDE FOR SAFER AND MORE EFFECTIVE IMMUNOTHERAPIES

The present invention provides polynucleotides and viral vectors for transfection of a mammalian host cell, preferably lentiviral vectors, encoding at least one CAR (chimeric antigen receptors)and a promoter from the Wiskott-Aldrich syndrome locus, in particular the promoter of SEQ. ID NO 1, operabl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MUNOZ FERNÁNDEZ, Pilar, MALDONADO PÉREZ, Noella, MARTIN MOLINA, Francisco, TRISTÁN MANZANO, María, BENABDELLAH EL KHLANJI, Karim
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The present invention provides polynucleotides and viral vectors for transfection of a mammalian host cell, preferably lentiviral vectors, encoding at least one CAR (chimeric antigen receptors)and a promoter from the Wiskott-Aldrich syndrome locus, in particular the promoter of SEQ. ID NO 1, operably linked to the CAR in order to drive its expression.